SC Individualized dosage.
Adult Replacement therapy: Adult onset GHD Initially 0.1-0.3 mg daily, to be increased gradually at mthly intervals. Max maintenance dose: 1 mg daily.
Childhood onset GHD Restart w/ 0.2-0.5 mg daily w/ subsequent dose adjustment on the basis of insulin-like growth factor (IGF-I) conc determination.
Childn GHD 0.025-0.035 mg/kg daily or 0.7-1 mg/m
2 daily.
Turner syndrome 0.045-0.067 mg/kg daily or 1.3-2 mg/m
2 daily.
Chronic renal disease 0.05 mg/kg daily or 1.4 mg/m
2 daily.
Born SGA 0.035 mg/kg daily or 1 mg/m
2 daily.